2 minutos

Algunos medicamentos alteran las fibras musculares y producen dolor y pueden ser reemplazados por otros con menos efectos secundarios.

Si tienes dolores musculares y estás tomando medicamentos para la tensión arterial o el colesterol, como Estatinas o IECAs, y tienes dolores musculares, debes pedirle a tu médico que considere alternativas.

Referencias:

Cranney, Ann,M.D., M.Sc. Is there a new role for angiotensin-converting-enzyme inhibitors in elderly patients? Canadian Medical Association.Journal 2007 Oct 09;177(8):891-2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995157/

Rundek T, Naini A, Sacco R, Coates K, DiMauro S. Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke. Arch Neurol 2004 Jun;61(6):889-892.  https://www.ncbi.nlm.nih.gov/pubmed/15210526

Päivä H, Thelen KM, Van Coster R, Smet J, De Paepe B, Mattila KM, et al. High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial. Clin Pharmacol Ther 2005 Jul;78(1):60-68. https://www.ncbi.nlm.nih.gov/pubmed/16003294

Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events. N Engl J Med 2008;358(15):1547-1559. http://www.nejm.org/doi/full/10.1056/NEJMoa0801317

Toto RD, Mitchell HC, Lee H, Milam C, Pettinger WA. Reversible Renal Insufficiency due to Angiotensin Converting Enzyme Inhibitors in Hypertensive Nephrosclerosis. Ann Intern Med. 1991;115:513–519. doi: 10.7326/0003-4819-115-7-513  https://www.ncbi.nlm.nih.gov/pubmed/1883120

KIFOR I, MOORE T, FALLO F,  SPERLING E, YEN C, MENACHERY A, WILLIAMS G.  Potassium-Stimulated Angiotensin Release from Superfused Adrenal Capsules and Enzymatically Dispersed Cells of the Zona Glomerulosa Endocrinology, Volume 129, Issue 2, 1 August 1991, Pages 823–831, https://doi.org/10.1210/endo-129-2-823 https://www.ncbi.nlm.nih.gov/pubmed/1855477

Lunde, H., Hedner, T., Samuelsson, O., Lotvall, J., Andren, L., Lindhom, L., & Wilholm, B. E. (1994). Dyspnoea, asthma, and bronchospasm in relation to treatment with angiotensin converting enzyme inhibitors. BMJ : British Medical Journal, 308(6920), 18. http://dx.doi.org.ezproxy.unbosque.edu.co/10.1136/bmj.308.6920.18 https://www.ncbi.nlm.nih.gov/pubmed/8298346

Effect of statins on skeletal muscle function.Parker BA, Capizzi JA, Grimaldi AS, Clarkson PM, Cole SM, Keadle J, Chipkin S, Pescatello LS, Simpson K, White CM, Thompson PD – Circulation – January 1, 2013; 127 (1); 96-103. https://www.ncbi.nlm.nih.gov/pubmed/23183941

Milly A van, d. P., Poortvliet, R. K. E., Sophie C E van, B., Wendy P J den, E., van Peet, P.,G., de Ruijter, W., . . . Gussekloo, J. (2016). Statin use and self-reported hindering muscle complaints in older persons: A population based study. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166857

James M. Backes, Janelle F. Ruisinger, Cheryl A. Gibson, Patrick M. Moriarty, Statin-associated muscle symptoms—Managing the highly intolerant, Journal of Clinical Lipidology, Volume 11, Issue 1, 2017, Pages 24-33. http://www.sciencedirect.com/science/article/pii/S1933287417300119